MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood
- Creator: Cox, Mathew B. , Cairns, Murray J. , ANZgene Multiple Sclerosis Genetics Consortium , Gandhi, Kaushal S. , Carroll, Adam P. , Moscovis, Sophia , Stewart, Graeme J. , Broadley, Simon , Scott, Rodney J. , Booth, David R. , Lechner-Scott, Jeannette
- Resource Type: journal article
- Date: 2010
The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis
- Creator: Gandhi, Kaushal S. , McKay, Fiona C. , Danoy, Patrick , Stewart, Graeme J. , Broadley, Simon , Moscato, Pablo , Lechner-Scott, Jeannette , Scott, Rodney J. , Booth, David R. , ANZgene Multiple Sclerosis Genetics Consortium , Cox, Mathew , Riveros, Carlos , Armstrong, Nicola , Heard, Robert N. , Vucic, Steve , Williams, David W. , Stankovich, Jim , Brown, Matthhew
- Resource Type: journal article
- Date: 2010
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci
- Creator: Patsopoulos, Nikolaos A. , de Bakker, Paul I. W. , Kappos, Ludwig , Miller, David , Montalbán, Javier , Polman, Chris H. , Freedman, Mark S. , Hartung, Hans-Peter , Arnason, Barry G. W. , Comi, Giancarlo , Cook, Stuart , Filippi, Massimo , Esposito, Federica , Goodin, Douglas S. , Jeffery, Douglas , O'Connor, Paul , Ebers, George C. , Langdon, Dawn , Reder, Anthony T. , Traboulsee, Anthony , Zipp, Frauke , Schimrigk, Sebastian , Hillert, Jan , Reischl, Joachim , Bahlo, Melanie , Booth, David R. , Broadley, Simon , Brown, Matthew A. , Browning, Brian L. , Browning, Sharon R. , Butzkueven, Helmut , Carroll, William M. , Chapman, Caron , Foote, Simon J. , Lehr, Stephan , Griffiths, Lyn , Kermode, Allan G. , Kilpatrick, Trevor J. , Lechner-Scott, Jeannette , Marriott, Mark , Mason, Deborah , Moscato, Pablo , Heard, Robert N. , Pender, Michael P. , Perreau, Victoria M. , Bauer, David , Perera, Devindri , Rubio, Justin P. , Scott, Rodney J. , Slee, Mark , Stankovich, Jim , Stewart, Graeme J. , Taylor, Bruce V. , Tubridy, Niall , Willoughby, Ernest , Wiley, James , Heubach, Jürgen , Matthews, Paul , Boneschi, Filippo M. , Compston, Alastair , Haines, Jonathan , Hauser, Stephen L. , McCauley, Jacob , Ivinson, Adrian , Oksenberg, Jorge R. , Pericak-Vance, Margaret , Sawcer, Stephen J. , Sandbrink, Rupert , De Jager, Philip L. , Hafler, David A. , Pohl, Christoph , Edan, Gilles
- Resource Type: journal article
- Date: 2011
Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility
- Creator: Ma, Gerry Z. M. , Stankovich, Jim , Browning, Sharon R. , Butzkueven, Helmut , Carroll, William M. , Danoy, Patrick , Foote, Simon J. , Griffiths, Lyn , Heard, Robert N. , Kermode, Allan G. , Lechner-Scott, Jeannette , Moscato, Pablo , Kilpatrick, Trevor J. , Perreau, Victoria M. , Scott, Rodney J. , Slee, Mark , Stewart, Graeme J. , Taylor, Bruce V. , Wiley, James , Binder, Michele D. , Field, Judith , Bahlo, Melanie , Booth, David R. , Broadley, Simon , Brown, Matthew A. , Browning, Brian L.
- Resource Type: journal article
- Date: 2011
Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects
- Creator: Lill, Christina M. , Liu, Tian , Blaschke, Paul , Winkelmann, Alexander , Gerdes, Lisa-Ann , Luessi, Felix , Fernadez, Oscar , Izquierdo, Guillermo , Antiguedad, Alfredo , Hoffjan, Sabine , Cournu-Rebeix, Isabelle , Gromoller, Silvana , Schjeide, Brit-Maren M. , Faber, Hans , Liebsch, Maria , Meissner, Esther , Chanvillard, Coralie , Touze, Emmauel , Pico, Fernando , Corcia, Philippe , Bahlo, Melanie , Booth, David R. , Broadley, Simon , Roehr, Johannes T. , Brown, Matthew A. , Browning, Brian L. , Browning, Sharon R. , Butzkueven, Helmut , Carroll, William M. , Cox, Mathew B. , Chapman, Caron , Clarke, Glynnis , Danoy, Patrick , Drysdale, Karen , Akkad, Denis A. , Field, Judith , Foote, Simon J. , Greer, Judith M. , Griffiths, Lyn R. , Hadler, Johanna , Jensen, Cathy J. , Johnson, Laura J. , Kermode, Allan G. , Heard, Robert N. , Kilpatrick, Trevor J. , Damotte, Vincent , Lechner-Scott, Jeanette , Marriott, Mark , Mason, Deborah , Moscato, Pablo , Pender, Michael P. , Perreau, Victoria M. , Rubio, Justin P. , Scott, Rodney J. , Slee, Mark , Stankovich, Jim , Alcina, Antonio , Stewart, Graeme J. , Tajouri, Lofti , Taylor, Bruce V. , Wiley, James , Wilkins, Ella J. , Dörner, Thomas , Steinhagen-Thiessen, Elisabeth , Baeckman, Lars , Heekeren, Hauke R. , Li, Shu-Chen , Ortiz, Miguel A. , Lindenberger, Ulman , Chan, Andrew , Hartung, Hans-Peter , Aktas, Orhan , Lohse, Peter , Kümpfel, Tania , Kubisch, Christian , Epplen, Joerg T. , Zettl, Uwe K. , Fontaine, Bertrand , Arroyo, Rafa , Vandenbroeck, Koen , Matesanz, Fuencisla , Urcelay, Elena , Bertram, Lars , Zipp, Frauke , Lopez de Lapuente, Aitzkoa
- Resource Type: journal article
- Date: 2012
Interleukin-6 gene promoter-572 C allele may play a role in rate of disease progression in multiple sclerosis
- Creator: Yan, Jun , Liu, Jia , Mason, Deborah , Griffiths, Lyn , Moscato, Pablo , Slee, Mark , Taylor, Bruce , Wiley, James , Field, Judith , Butzkueven, Helmut , Kilpatrick, Trevor J. , Csurhes, Peter A. , Lin, Clement Yihao , Pender, Michael P. , McCombe, Pamela A. , Greer, Judith M. , Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZGene), , Scott, Rodney J. , Lechner-Scott, Jeannette , Brown, Matthew A. , Booth, David R. , Stewart, Graeme J. , Broadley, Simon
- Resource Type: journal article
- Date: 2012
Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season
- Creator: Parnell, Grant P. , Gatt, Prudence N. , Liddle, Christopher , Slee, Mark , Vucic, Steve , Stewart, Graeme J. , Booth, David R. , McKay, Fiona C. , Schibeci, Stephen , Krupa, Malgorzata , Powell, Joseph E. , Visscher, Peter M. , Montgomery, Grant W. , Lechner-Scott, Jeannette , Broadley, Simon
- Resource Type: journal article
- Date: 2014
The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells
- Creator: Shahijanian, Fernando , Parnell, Grant P. , Baxter, Alan , Kermode, Allan , Carroll, William , Butzkueven, Helmut , Booth, David , Stewart, Graeme , Vucic, Steve , Wiley, James , Field, Judith , Tajouri, Lotti , McKay, Fiona C. , Griffiths, Lyn , Barnett, Michael , Scott, Rodney , Lechner-Scott, Jeannette , Moscato, Pablo , Broadley, Simon , Slee, Mark , Kilpatrick, Trevor , Taylor, Bruce , Charlesworth, Jac , Gatt, Prudence N. , Brown, Matt , Mason, Deborah , Stewart, Graeme J. , Booth, David R. , Shojoei, Maryam , O'Connor, Kate S. , Schibeci, Stephen D. , Brilot, Fabienne , Liddle, Christopher , Batten, Marcel
- Resource Type: journal article
- Date: 2014
The MS risk allele of CD40 is associated with reduced cell-membrane bound expression in antigen presenting cells: implications for gene function
- Creator: Field, Judith , Shahijanian, Fernando , Butzkueven, Helmut , Booth, David , Baxter, Alan , Kermode, Allan G. , Taylor, Bruce , Booth, David R. , Mason, Deborah , Stewart, Graeme J. , Charlesworth, Jac , Schibeci, Stephen , Wiley, James , Lechner-Scott, Jeannette , Tajouri, Lotti , Griffiths, Lyn , Slee, Mark , Brown, Matthew A. , Moscato, Pablo , Scott, Rodney J. , Broadley, Simon , Johnson, Laura , Vucic, Steve , Kilpatrick, Trevor , Carroll, William M. , Gresle, Melissa , Laverick, Louise , Parnell, Grant , Stewart, Graeme , McKay, Fiona
- Resource Type: journal article
- Date: 2015
Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination
- Creator: Ramanathan, Sudarshini , Mohammad, Shekeeb , Henderson, Andrew P. D. , Barnett, Michael Harry , Reddel, Stephen W. , Brilot, Fabienne , Dale, Russell C. , Tantsis, Esther , Nguyen, Tina Kim , Merheb, Vera , Fung, Victor S. C. , White, Owen Bruce , Broadley, Simon , Lechner-Scott, Jeannette , Vucic, Steve
- Resource Type: journal article
- Date: 2018
Common genetic variation within miR-146a predicts disease onset and relapse in multiple sclerosis
- Creator: Zhou, Yuan , Chen, Ming , Dear, Keith , Dwyer, Terry , Blizzard, Leigh , Simpson, Steve , Taylor, Bruce V. , Broadley, Simon , Kilpatrick, Trevor , Williams, David , Lechner-Scott, Jeanette , Shaw, Cameron , Chapman, Caron , Coulthard, Alan , Valery, Patricia , Valery, P , Taylor, BV , Lucas, Robyn M. , Charlesworth, Jac C. , Blackburn, Nicholas , van der Mei, Ingrid , Ponsonby, Anne-Louise
- Resource Type: journal article
- Date: 2018
Onset symptoms, Tobacco smoking, and progressive-onset phenotype are associated with a delayed onset of multiple sclerosis, and marijuana use with an earlier onset
- Creator: Tao, Chunrong , Simpson, Steve , Kilpatrick, Trevor , Williams, David , Lechner-Scott, Jeanette , Shaw, Cameron , Chapman, Caron , Coulthard, Alan , Pender, Michael P. , Valery, Patricia , Taylor, Bruce V. , Blizzard, Leigh , Lucas, Robyn M. , Ponsonby, Anne-Louise , Broadley, Simon , van der Mei, Ingrid , Dear, Keith , Dwyer, Terry
- Resource Type: journal article
- Date: 2018
Sun exposure across the life course significantly modulates early multiple sclerosis clinical course
- Creator: Simpson, Steve , Van Der Mei, Ingrid , Williams, David , Lechner-Scott, Jeanette , Shaw, Cameron , Chapman, Caron , Coulthard, Alan , Pender, Michael P. , Valery, Patricia , Lucas, Robyn M. , Ponsonby, Anne-Louise , Broadley, Simon , Blizzard, Leigh , Taylor, Bruce , Dear, Keith , Dwyer, Terry , Kilpatrick, Trevor
- Resource Type: journal article
- Date: 2018
Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination
- Creator: Tea, Fiona , Lopez, Joseph A. , Tantsis, Esther M. , Yiu, Eppie M. , Vucic, Steve , Henderson, Andrew P. D. , Fok, Anthony , Fraser, Clare L. , Lechner-Scott, Jeanette , Reddel, Stephen W. , Broadley, Simon , Barnett, Michael H. , Ramanathan, Sudarshini , Brown, David A. , Lunemann, Jan D. , Dale, Russell C. , Brilot, Fabienne , Australasian and New Zealand MOG Study Group, , Merheb, Vera , Lee, Fiona X. Z. , Zou, Alicia , Pilli, Deepti , Patrick, Ellis , van der Walt, Anneke , Monif, Mastura
- Resource Type: journal article
- Date: 2019
The effect of emerging nutraceutical interventions for clinical and biological outcomes in multiple sclerosis: A systematic review
- Creator: Marx, Wolfgang , Hockey, Meghan , McGuinness, Amelia J. , Lane, Melissa , Christodoulou, John , van der Mei, Ingrid , Berk, Michael , Dean, Olivia M. , Taylor, Bruce , Broadley, Simon , Lechner-Scott, Jeannette , Jacka, Felice N. , Lucas, Robyn M. , Ponsonby, Anne-Louise
- Resource Type: journal article
- Date: 2020
Long-term trajectories of employment status, workhours and disability support pension status, after a first episode of CNS demyelination
- Creator: Zarghami, Amin , van der Mei, Ingrid , Taylor, Bruce V. , AusLong Investigator Group, , Hussain, Mohammad Akhtar , Claflin, Suzi B. , Bessing, Barnabas , Simpson-Yap, Steve , Ponsonby, Anne-Louise , Lechner-Scott, Jeanette , Broadley, Simon , Blizzard, Leigh
- Resource Type: journal article
- Date: 2022
Validation of a Flow Cytometry Live Cell-Based Assay to Detect Myelin Oligodendrocyte Glycoprotein Antibodies for Clinical Diagnostics
- Creator: Lopez, Joseph A. , Houston, Samuel D. , Denkova, Martina , Lechner-Scott, Jeannette , van der Walt, Anneke , Barnett, Michael H. , Reddel, Stephen W. , Broadley, Simon , Ramanathan, Sudarshini , Dale, Russel C. , Brown, David A. , Brilot, Fabienne , Tea, Fiona , Merheb, Vera , Lee, Fiona X. Z. , Smith, Sandy , McDonald, David , Zou, Alicia , Liyanage, Ganesha , Pilli, Deepti
- Resource Type: journal article
- Date: 2022
Examining the environmental risk factors of progressive-onset and relapsing-onset multiple sclerosis: recruitment challenges, potential bias, and statistical strategies
- Creator: Li, Ying , Saul, Alice , Eichau, Sara , Onofrj, Marco , Ozakbas, Serkan , Horakova, Dana , Havrdova, Eva Kubala , Grand'Maison, Francois , Alroughani, Raed , Gerlach, Oliver , Amato, Maria Pia , Altintas, Ayse , Taylor, Bruce , Girard, M , Duquette, P , Blanco, Y , Ramo-Tello, C , Laureys, G , Kalincik, T , Khoury, SJ , Shaygannejad, V , Etemadifar, M , Singhal, B , Ponsonby, Anne-Louise , Mrabet, S , Foschi, M , Habek, M , John, N , Hughes, S , McCombe, P , Ampapa, R , van der Walt, A , Butzkueven, H , de Gans, K , Simpson-Yap, Steve , McGuigan, C , Oreja-Guevara, C , Sa, MJ , Petersen, T , Al-Harbi, T , Sempere, AP , Van Wijmeersch, B , Grigoriadis, N , Prevost, J , Gray, O , Blizzard, Leigh , Castillo-Trivino, T , Macdonell, R , Lugaresi, A , Sajedi, SA , van der Mei, I , Broadley, Simon , Lechner-Scott, Jeannette , Karabudak, Rana , Patti, Francesco
- Resource Type: journal article
- Date: 2024